About: Isolation and Characterization of Neural Crest Stem Cells from Adult Human Hair Follicles

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	This paper describes the isolation of adult neural crest stem cells from human hair follicles using the method based on mechanical dissection of the follicle, its explantation into tissue culture and emigration of stem cells. Characterization of isolated cells is based on detection of neural crest and general stem cell markers (on protein and mRNA levels). All the presented results strongly support the neural crest stem cell identity and multipotency of isolated adult human cells. These cells thus could be a good candidate for stem cell therapy, especially because of the easy accessibility of donor tissue. This paper describes the isolation of adult neural crest stem cells from human hair follicles using the method based on mechanical dissection of the follicle, its explantation into tissue culture and emigration of stem cells. Characterization of isolated cells is based on detection of neural crest and general stem cell markers (on protein and mRNA levels). All the presented results strongly support the neural crest stem cell identity and multipotency of isolated adult human cells. These cells thus could be a good candidate for stem cell therapy, especially because of the easy accessibility of donor tissue. (en)
Title	Isolation and Characterization of Neural Crest Stem Cells from Adult Human Hair Follicles Isolation and Characterization of Neural Crest Stem Cells from Adult Human Hair Follicles (en)
skos:prefLabel	Isolation and Characterization of Neural Crest Stem Cells from Adult Human Hair Follicles Isolation and Characterization of Neural Crest Stem Cells from Adult Human Hair Follicles (en)
skos:notation	RIV/00216208:11110/10:6255!RIV11-MSM-11110___
http://linked.open...avai/riv/aktivita	P S Z
http://linked.open...avai/riv/aktivity	P(LC06061), S, Z(MSM0021620806)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Grim, Miloš Krejčí, Eliška
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 1. lékařská fakulta
http://linked.open...dnocenehoVysledku	265008
http://linked.open...ai/riv/idVysledku	RIV/00216208:11110/10:6255
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	neural crest; stem cells; human hair follicle; expression profile; EPI-NCSCs; nestin expression; progenitor cells; self-renewal; in-vitro; transcription; pluripotent; skin; differentiation; generation (en)
http://linked.open.../riv/klicoveSlovo	stem cells skin transcription EPI-NCSCs human hair follicle nestin expression pluripotent self-renewal generation differentiation expression profile progenitor cells neural crest in-vitro
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[CFE9D6B3F307]
http://linked.open...i/riv/nazevZdroje	Folia Biologica
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	Center of Cell Invasiveness in Embryonic Development and Tumour Metastases
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	56
http://linked.open...iv/tvurceVysledku	Grim, Miloš Krejčí, Eliška
http://linked.open...ain/vavai/riv/wos	000281924500002
http://linked.open...n/vavai/riv/zamer	Molekulární biologie a patologie buňky za normy a u vybraných klinicky závažných patologických procesů
issn	0015-5500
number of pages	9 (xsd:int)
http://localhost/t...ganizacniJednotka	11110

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