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  • All consecutive patients from one country (n 119, period 19772009) undergoing permanent epicardial pacemaker implantation at 18 years of age (median 1.8 years, inter-quartile range 0.36.4 years) were studied retrospectively. Median patient follow up was 6.4 years (inter-quartile range 2.911.1 years); 207 generators, 89 atrial and 153 ventricular pacing leads were implanted. The probability of absence of any pacing system dysfunction was 70.1 and 47.2 at 5 and 10 years after implantation, respectively. Overall probability of continued epicardial pacing was 92.8 and 76.1 at 5 and 10 years, respectively, and increased in the recent implantation era (post-2000, P 0.04). The use of steroid-eluting leads decreased the risk of exit block with a hazard ratio (HR) of 0.20 [95 confidence interval (CI) 0.090.44, P 0.001)]. The use of bipolar Medtronic 4968 leads reduced the risk of surgical reintervention because of fracture, insulation break, outgrowth or exit block in comparison to the unipolar 4965 lead design (HR 0.12, 95 CI 0.040.40, P 0.001). The AutoCapture feature (HR 0.08, 95 CI 0.020.36, P 0.001) and steroid-eluting leads (HR 0.30, 95 CI 0.110.84, P 0.021) decreased the risk of battery depletion. The probability of continued epicardial pacing in children was 76 at 10 years after implantation, increased for implantation in recent years, and allowed transvenous pacing to be deferred to a significantly greater age. The use of bipolar steroid-eluting leads and of a beat-to-beat capture tracking feature significantly increased pacing system longevity and decreased the need for surgical reinterventions.
  • All consecutive patients from one country (n 119, period 19772009) undergoing permanent epicardial pacemaker implantation at 18 years of age (median 1.8 years, inter-quartile range 0.36.4 years) were studied retrospectively. Median patient follow up was 6.4 years (inter-quartile range 2.911.1 years); 207 generators, 89 atrial and 153 ventricular pacing leads were implanted. The probability of absence of any pacing system dysfunction was 70.1 and 47.2 at 5 and 10 years after implantation, respectively. Overall probability of continued epicardial pacing was 92.8 and 76.1 at 5 and 10 years, respectively, and increased in the recent implantation era (post-2000, P 0.04). The use of steroid-eluting leads decreased the risk of exit block with a hazard ratio (HR) of 0.20 [95 confidence interval (CI) 0.090.44, P 0.001)]. The use of bipolar Medtronic 4968 leads reduced the risk of surgical reintervention because of fracture, insulation break, outgrowth or exit block in comparison to the unipolar 4965 lead design (HR 0.12, 95 CI 0.040.40, P 0.001). The AutoCapture feature (HR 0.08, 95 CI 0.020.36, P 0.001) and steroid-eluting leads (HR 0.30, 95 CI 0.110.84, P 0.021) decreased the risk of battery depletion. The probability of continued epicardial pacing in children was 76 at 10 years after implantation, increased for implantation in recent years, and allowed transvenous pacing to be deferred to a significantly greater age. The use of bipolar steroid-eluting leads and of a beat-to-beat capture tracking feature significantly increased pacing system longevity and decreased the need for surgical reinterventions. (en)
Title
  • Permanent epicardial pacing in children: long-term results and factors modifying outcome
  • Permanent epicardial pacing in children: long-term results and factors modifying outcome (en)
skos:prefLabel
  • Permanent epicardial pacing in children: long-term results and factors modifying outcome
  • Permanent epicardial pacing in children: long-term results and factors modifying outcome (en)
skos:notation
  • RIV/00064203:_____/12:8009!RIV13-MZ0-00064203
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MZ0FNM2005)
http://linked.open...iv/cisloPeriodika
  • 4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 158269
http://linked.open...ai/riv/idVysledku
  • RIV/00064203:_____/12:8009
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Pacing; Epicardial; Children; Atrioventricular block; Congenital heart disease; congenital heart-disease; dual-chamber; cardiac resynchronization; venous obstruction; pediatric-patients; young; leads; experience; pacemaker; site (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [39080370683E]
http://linked.open...i/riv/nazevZdroje
  • Europace
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 14
http://linked.open...iv/tvurceVysledku
  • Gebauer, Roman
  • Janoušek, Jan
  • Matějka, Tomáš
  • Tláskal, Tomáš
  • Gebauer, R. A.
  • Kubuš, Peter
  • Materna, Ondřej
http://linked.open...ain/vavai/riv/wos
  • 000302301800012
http://linked.open...n/vavai/riv/zamer
issn
  • 1099-5129
number of pages
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