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| rdf:type
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| Description
| - Selata po odstavu byla infikována shigatoxigenním kmenem E. coli (STEC). Selatům pokusné skupiny byl po dobu pokusu intramuskulárně aplikován kolistin. U obou skupin bylo pozorováno osídlení střeva STEC. STEC byly detekovány v mízních uzlinách selat neošetřených kolistinem. Ve skupině ošetřených kolistinem (11 selat) došlo k onemocnění edémovou nemocí u 10 selat a 8 z nich uhynulo nebo bylo utraceno ante finem. V kontrolní skupině (11 selat) onemocnělo edémovou nemocí 5 selat a 4 z nich uhynula nebo byla utracena ante finem. Předpokládáme, že kolistin destrukcí bakteriální stěny vyvolal náhlé uvolnění shiga toxinu z buněk STEC pronikající přes stěnu střeva. To může vysvětlovat těžší průběh edémové nemoci u selat ošetřených kolistinem. U selat neošetřených kolistinem, i když byly STEC ve vysokých počtech detekovány v mezenteriálních mízních uzlinách, nebyl toxin uvolněn tak náhle, protože stěny bakteriálních buněk nebyly poškozeny. (cs)
- Piglets after weaning were challenged by Shiga toxigenic E. coli strain (STEC). Piglets of experimental group were intramuscularly treated with colistin. After the challenge, colonisation of the intestines was observed in both group of piglets. STEC were detected in the mesenteric lymph nodes of untreated piglets. In colistin treated group of piglets (11 piglets) oedema disease developed in 10 piglets, eigt of which died or were euthanized ante finem. In the untreated group (11 piglets) oedema disease developed in five piglets, four of which died or were euthanized. We there propose, that the STEC lysed by colistin suddenly released the shiga toxin from bacterial cells immediately after their passage through the intestinal wall. That could explain a more severe course of oedema disease in the treated piglets. Even though high amounts of STEC were presented in the lymph nodes of untreted piglets, the toxin was not released abruptly because the bacterial cells were not damaged.
- Piglets after weaning were challenged by Shiga toxigenic E. coli strain (STEC). Piglets of experimental group were intramuscularly treated with colistin. After the challenge, colonisation of the intestines was observed in both group of piglets. STEC were detected in the mesenteric lymph nodes of untreated piglets. In colistin treated group of piglets (11 piglets) oedema disease developed in 10 piglets, eigt of which died or were euthanized ante finem. In the untreated group (11 piglets) oedema disease developed in five piglets, four of which died or were euthanized. We there propose, that the STEC lysed by colistin suddenly released the shiga toxin from bacterial cells immediately after their passage through the intestinal wall. That could explain a more severe course of oedema disease in the treated piglets. Even though high amounts of STEC were presented in the lymph nodes of untreted piglets, the toxin was not released abruptly because the bacterial cells were not damaged. (en)
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| Title
| - The effect of intramuscular administration of colistin on the development and course of experimentally induced oedema disease in weaned piglets
- The effect of intramuscular administration of colistin on the development and course of experimentally induced oedema disease in weaned piglets (en)
- Vliv intramuskulární aplikace kolistinu na vznik a průběh experimentálně vyvolané edémové nemoci selat po odstavu (cs)
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| skos:prefLabel
| - The effect of intramuscular administration of colistin on the development and course of experimentally induced oedema disease in weaned piglets
- The effect of intramuscular administration of colistin on the development and course of experimentally induced oedema disease in weaned piglets (en)
- Vliv intramuskulární aplikace kolistinu na vznik a průběh experimentálně vyvolané edémové nemoci selat po odstavu (cs)
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| skos:notation
| - RIV/00027162:_____/08:#0000340!RIV09-MZE-00027162
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/00027162:_____/08:#0000340
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - Escherichia coli; ED; STEC; colonising factors (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
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| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
| |
| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Alexa, Pavel
- Hamřík, Jaroslav
- Konstantinová, Lucie
- Kulich, Pavel
- Kummer, Vladimír
- Mašková, Jarmila
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| http://linked.open...ain/vavai/riv/wos
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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