About: Diagnosis of Alzheimer disease based on detections of complexes of amyloid beta peptide and of some endogenous substances in cerebrospinal fluid     Goto   Sponge   Distinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

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Description
  • After developments of new highly sensitive methods (via ELISA and surface plasmon resonance biosensors) , we will evaluate the levels of two complexes of amyloid beta peptides with either mitochondrial enzyme 17beta-hydroxysteroid dehydrogenase type 10 or protein tau in cerebrospinal fluids of demented and nondemented people. The results will be compared with those of triplet (amyloid beta peptide 1-42, total tau and phospho-tau levels by means of kits). (en)
  • Po zavedení nových citlivých metod (ELISA a senzory s povrchovými plazmony) budou v mozkomíšním moku dementních a nedementních lidí testovány hladiny dvou komplexů peptidu amyloidu beta (s mitochondriálním enzymem 17beta-hydroxysteroidovou dehydrogenázou typu 10 a proteinem tau). Pomocí kitů budou dále stanoveny hladiny tripletu (amyloid beta 1-42, celkový tau a fosforylovaný tau).
Title
  • Diagnosis of Alzheimer disease based on detections of complexes of amyloid beta peptide and of some endogenous substances in cerebrospinal fluid (en)
  • Diagnostika Alzheimerovy nemoci založená na detekci komplexů peptidu amyloidu beta s některými endogenními látkami v cerebrospinální tekutině
skos:notation
  • NT11225
http://linked.open...avai/cep/aktivita
http://linked.open...kovaStatniPodpora
http://linked.open...ep/celkoveNaklady
http://linked.open...datumDodatniDoRIV
http://linked.open...i/cep/druhSouteze
http://linked.open...ep/duvernostUdaju
http://linked.open.../cep/fazeProjektu
http://linked.open...ai/cep/hlavniObor
http://linked.open...hodnoceniProjektu
http://linked.open...vai/cep/kategorie
http://linked.open.../cep/klicovaSlova
  • biomarker; Alzheimer disease; cerebrospinal fluid (en)
http://linked.open...ep/partnetrHlavni
http://linked.open...inujicichPrijemcu
http://linked.open...cep/pocetPrijemcu
http://linked.open...ocetSpoluPrijemcu
http://linked.open.../pocetVysledkuRIV
http://linked.open...enychVysledkuVRIV
http://linked.open...lneniVMinulemRoce
http://linked.open.../prideleniPodpory
http://linked.open...iciPoslednihoRoku
http://linked.open...atUdajeProjZameru
http://linked.open.../vavai/cep/soutez
http://linked.open...usZobrazovaneFaze
http://linked.open...ai/cep/typPojektu
http://linked.open...ep/ukonceniReseni
http://linked.open...ep/zahajeniReseni
http://linked.open...jektu+dodavatelem
  • V souladu s anotací a termíny projekt vedl k zavedení nových biologických markerů k detekci demence Alzheimerova typu..Výsledky byly publikovány v časopisech s IF u nás I v zahraničí s dedikací IGA MZ nad rámec plánovaných cílů. (cs)
  • In accord with the annotations and the terms, the project led to the introduction of new biological markers for detection of dementia Alzheimer's type. The publications with IF in CR and abroad with dedication to IGA MZ exceeded the project plans. (en)
http://linked.open...tniCyklusProjektu
http://linked.open.../cep/klicoveSlovo
  • biomarker
  • Alzheimer disease
is http://linked.open...vavai/cep/projekt of
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