About: Diagnosis of Alzheimer disease based on detections of complexes of amyloid beta peptide and of some endogenous substances in cerebrospinal fluid     Goto   Sponge   Distinct   Permalink

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  • Po zavedení nových citlivých metod (ELISA a senzory s povrchovými plazmony) budou v mozkomíšním moku dementních a nedementních lidí testovány hladiny dvou komplexů peptidu amyloidu beta (s mitochondriálním enzymem 17beta-hydroxysteroidovou dehydrogenázou typu 10 a proteinem tau). Pomocí kitů budou dále stanoveny hladiny tripletu (amyloid beta 1-42, celkový tau a fosforylovaný tau). (cs)
  • After developments of new highly sensitive methods (via ELISA and surface plasmon resonance biosensors) , we will evaluate the levels of two complexes of amyloid beta peptides with either mitochondrial enzyme 17beta-hydroxysteroid dehydrogenase type 10 or protein tau in cerebrospinal fluids of demented and nondemented people. The results will be compared with those of triplet (amyloid beta peptide 1-42, total tau and phospho-tau levels by means of kits). (en)
Title
  • Diagnostika Alzheimerovy nemoci založená na detekci komplexů peptidu amyloidu beta s některými endogenními látkami v cerebrospinální tekutině (cs)
  • Diagnosis of Alzheimer disease based on detections of complexes of amyloid beta peptide and of some endogenous substances in cerebrospinal fluid (en)
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  • biomarker; Alzheimer disease; cerebrospinal fluid (en)
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