About: Chromatin Regulation of Phaseolin Transcrption     Goto   Sponge   Distinct   Permalink

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  • Nalezení pozitivních i negativních upstream faktorů vedoucích k aktivaci transkripce promoteru phas. (cs)
  • Phaseolin, a major seed storage protein of Phaseolus vulgaris is encoded by phaseolin (phas) gene. During seed development, phas is expressed at exceptionally high levels but it is fully repressed in all vegetative tissues. The establishment of a repressive chromatin structure and the presence of a nucleosome over three phased TATA boxes of the phas promoter is responsible for the lack of phas expression in vegetative tissue. Tranion from the phas promoter is enabled during early embryogenesis by a two-step process. Step 1 involves chromatin remodeling (by the B3 domain-containing tranion factor PvALF), that permits formation of a potentiated tranion complex. In step 2, tranional activation is initiated by an ABAinduced signal transduction cascade. The main goal of this proposal is to contribute to the explanation how changes in chromatin structure over the phas promoter are orchestrated to permit tranion. This will include search for proteins that interact with the effector to achieve chrom (en)
Title
  • Chromatin Regulation of Phaseolin Transcrption (en)
  • Regulace transkripce faseolinu na úrovni chromatinu (cs)
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  • phaseolin; chromatin; histon code; expression regulation; embryogenesis (en)
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