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  • Studie ALLHAT (Treatment to prevent heart attack trial) Randomizovaná dvojitě zaslepená studie týkající se morbidity a mortality ALLHAT (Antihypertensive and Lipid- Lowering Treatment to Prevent Heart Attack Trial) sledovala srovnání léčby novějšími léky: amlodipin 2.5-10 mg/d (blokátor kalciových kanálů) nebo lisinopril 10-40 mg/d (ACE-inhibitor) jako léčba první volby a thiazidové diuretikum chlortalidon 12,5-25 mg/d při léčbě mírné až střední hypertenze. (cs)
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