About: Sulbactam Pivoxil     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Sulbactam Pivoxil
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Sulbactam Pivoxil
UMLS_CUI
  • C0617130
CAS_Registry
  • 69388-79-0
FDA_UNII_Code
  • 2X0WTA96KX
Contributing_Source
  • FDA
Chemical_Formula
  • C14H21NO7S
FULL_SYN
  • PivsulbactamSYNCI
  • Hydroxymethyl (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate pivalate (ester), 4,4-dioxideSNNCI
  • Sulbactam PivoxilPTNCI
  • SULBACTAM PIVOXILPTFDA2X0WTA96KX
  • CP-47904CNNCI
  • CP-47,904CNNCI
  • 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-, 4,4-dioxide, (2,2-dimethyl-1-oxopropoxy)methyl ester, (2S-cis)-SNNCI
DEFINITION
  • The pivoxil prodrug form of sulbactam, a semi-synthetic beta-lactamase inhibitor, with beta-lactam antibiotic adjuvant activity. After oral administration of sulbactam pivoxil, the ester bond is cleaved, releasing active sulbactam. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby blocking enzyme activity and preventing metabolism of other beta-lactam antibiotics by the enzyme.NCI
code
  • C96733
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