About: 10-Deacetyltaxol     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • 10-Deacetyltaxol
rdfs:subClassOf
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • 10-Deacetyltaxol
NSC_Code
  • 656201
UMLS_CUI
  • C0044663
CAS_Registry
  • 78432-77-6
Legacy_Concept_Name
  • _10-Deacetyltaxol
FULL_SYN
  • 10-DeacetyltaxolPTNCI
  • benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (2aR-(2aalpha,4beta,4abeta,6beta,9alpha(alphaR*,betaS*),11alpha,12alpha,12aalpha,12balpha))-SNNCI
  • 10-DeacetyltaxolSYDTPNSC0656201
DEFINITION
  • An analog of paclitaxel with antineoplastic activity. 10-Deacetyltaxol binds to and stabilizes the resulting microtubules, thereby inhibiting microtubule disassembly which results in cell- cycle arrest at the G2/M phase and apoptosis.NCI
code
  • C957
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