About: Technetium Tc-99m Hydroxydiphosphonate     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Technetium Tc-99m Hydroxydiphosphonate
rdfs:subClassOf
Semantic_Type
  • Indicator, Reagent, or Diagnostic Aid
Preferred_Name
  • Technetium Tc-99m Hydroxydiphosphonate
UMLS_CUI
  • C0075952
PDQ_Open_Trial_Search_ID
  • 687964
PDQ_Closed_Trial_Search_ID
  • 687964
FULL_SYN
  • Tc-99m HydroxydiphosphonateABNCI
  • Technetium Tc-99m HydroxydiphosphonatePTNCI
  • 99mTc HDPABNCI
DEFINITION
  • A radioconjugate containing hydroxydiphosphonate (HDP) labeled with the metastable radioisotope technetium Tc (99mTc), with radioimaging activity. Upon intravenous administration, skeletal uptake of technetium Tc-99m HDP occurs as a function of skeletal blood flow and osteogenic activity. HDP has a specific affinity for hydroxyapatite crystals in bone where abnormal accumulation of increased osteoid mineralization has occurred. Labeling of HDP with 99mTc allows gamma scintigraphic imaging of areas of abnormal osteogenesis associated with malignant bone lesions.NCI
code
  • C94222
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