About: Leishmaniasis Infection Pathway

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Leishmaniasis Infection Pathway Goto Sponge Distinct Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Leishmaniasis Infection Pathway
rdfs:subClassOf	Infectious Disease Pathway
Semantic_Type	Functional Concept
Preferred_Name	Leishmaniasis Infection Pathway
UMLS_CUI	C2984302
KEGG_ID	hsa05140
ALT_DEFINITION	Leishmania is an intracellular protozoan parasite of macrophages that causes visceral, mucosal, and cutaneous diseases. The parasite is transmitted to humans by sandflies, where they survive and proliferate intracellularly by deactivating the macrophage. Successful infection of Leishmania is achieved by alteration of signaling events in the host cell, leading to enhanced production of the autoinhibitory molecules like TGF-beta and decreased induction of cytokines such as IL12 for protective immunity. Nitric oxide production is also inhibited. In addition, defective expression of major histocompatibility complex (MHC) genes silences subsequent T cell activation mediated by macrophages, resulting in abnormal immune responses.KEGG
FULL_SYN	LeishmaniasisPTKEGG Leishmaniasis Infection PathwayPTNCI
code	C91491
is someValuesFrom of	nodeID://b668811 nodeID://b668855 nodeID://b672604 nodeID://b672674 nodeID://b678256 nodeID://b678291 nodeID://b678346 nodeID://b678375 nodeID://b681885 nodeID://b682000 nodeID://b682053 nodeID://b682912 nodeID://b682999 nodeID://b683630 nodeID://b684495 nodeID://b684522 nodeID://b684681 nodeID://b684773 nodeID://b684826 nodeID://b684848 nodeID://b688154 nodeID://b688178 nodeID://b688206 nodeID://b688243 nodeID://b688332 nodeID://b688928 nodeID://b688949 nodeID://b688972 nodeID://b689006 nodeID://b689086 nodeID://b689188 nodeID://b693276 nodeID://b695053 nodeID://b695263 nodeID://b695587 nodeID://b696832 nodeID://b697158 nodeID://b700783 nodeID://b701313 nodeID://b705264 nodeID://b706810 nodeID://b711142 nodeID://b712434

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 83 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software