About: Chromomycin A3     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Chromomycin A3
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Antibiotic
Preferred_Name
  • Chromomycin A3
NSC_Code
  • 58514
UMLS_CUI
  • C0040563
CAS_Registry
  • 7059-24-7
FDA_UNII_Code
  • DVW027E7NL
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 39184
PDQ_Closed_Trial_Search_ID
  • 39184
Chemical_Formula
  • C57H82O26
Legacy_Concept_Name
  • Chromomycin_A3
CHEBI_ID
  • CHEBI:34638
FULL_SYN
  • Aburamycin BSYDTPNSC0058514
  • CHROMOMYCIN A3PTFDADVW027E7NL
  • CHROMOMYCIN A3SYDTPNSC0058514
  • Chromomycin A3PTNCI
  • Olivomycin D, 3B-O-(4-O-acetyl-2, 6-dideoxy-3-C-methyl-.alpha.-L-arabino-hexopyranosyl)-7-methyl- (9CI)SYDTPNSC0058514
  • Antibiotic from Streptomyces griseusSYNCI
  • Antibiotic B 599SYNCI
  • 3B-O-(4-O-Acetyl-2,6-dideoxy-3-C-methyl-alpha-L-arabino-hexopyranosyl)-7-methylolivomycin DSNNCI
  • Antibiotic from Streptomyces griseusSYDTPNSC0058514
  • Antibiotic 69895 ASYNCI
  • TOYOMYCINSYDTPNSC0058514
  • ToyomycinSYNCI
  • Olivomycin D, 3B-O-(4-O-Acetyl-2, 6-dideoxy-3-C-methyl-.alpha.-L-arabino-hexopyranosyl)-7-methyl- (9CI)SNNCI
DEFINITION
  • A glycosidic antineoplastic antibiotic isolated from the bacterium Streptomyces griseus. Chromomycin A3 reversibly binds to guanine-cytosine (G-C) base pairs in the minor groove of DNA, thereby inhibiting RNA synthesis. This agent is used as a fluorescent chromosome dye. (NCI04)NCI
code
  • C895
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