About: Ferumoxytol Non-Stoichiometric Magnetite     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Ferumoxytol Non-Stoichiometric Magnetite
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Inorganic Chemical
  • Indicator, Reagent, or Diagnostic Aid
Preferred_Name
  • Ferumoxytol Non-Stoichiometric Magnetite
NCI_META_CUI
  • CL415510
CAS_Registry
  • 1309-38-2
Accepted_Therapeutic_Use_For
  • Iron deficiency anemia
FDA_UNII_Code
  • CLH5FT6412
Contributing_Source
  • FDA
ALT_DEFINITION
  • A nanoparticle form of iron made in the laboratory that is being studied for use in iron replacement therapy, and as a contrast agent for magnetic resonance imaging. Contrast agents are substances that are injected into the body and taken up by certain tissues, making the tissues easier to see in imaging scans.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 377345
PDQ_Closed_Trial_Search_ID
  • 377345
Chemical_Formula
  • 3Fe.4O
CHEBI_ID
  • CHEBI:46726
FULL_SYN
  • FerumoxytolSYNCI
  • ferumoxytolPTNCI-GLOSSCDR0000390278
  • FERUMOXYTOL NON-STOICHIOMETRIC MAGNETITEPTFDACLH5FT6412
  • FerahemeBRNCI
  • Ferumoxytol Non-Stoichiometric MagnetitePTNCI
DEFINITION
  • A superparamagnetic iron oxide nanoparticle coated with a low molecular weight semi-synthetic carbohydrate, polyglucose sorbitol carboxymethyl ether, with potential anti-anemic and imaging properties. After intravenous administration, ferumoxytol replaces iron stores with fewer side effects compared to the use of oral iron. In addition, this agent generates T1 relaxation, producing a magnetic field and enhancing T2 relaxation, thereby darkening contrast media-containing structures in magnetic resonance imaging (MRI). Due to small particle size, ferumoxytol remains in the intravasculature for a prolonged period and so may be used as a blood pool agent.NCI
code
  • C87701
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