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AttributesValues
rdf:type
rdfs:label
  • Isepamicin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Isepamicin
UMLS_CUI
  • C0124008
CAS_Registry
  • 58152-03-7
FDA_UNII_Code
  • G7K224460P
Contributing_Source
  • FDA
Chemical_Formula
  • C22H43N5O12
CHEBI_ID
  • CHEBI:37951
FULL_SYN
  • (2S)-3-amino-N-((1R,2S,3S,4R,5S)-5-amino-4-[(6-amino-6-deoxy-D-glucopyranosyl)oxy]-2-{[3-deoxy-4-C-methyl-3-(methylamino)-L-arabinopyranosyl]oxy}-3-hydroxycyclohexyl)-2-hydroxypropanamideSYNCI
  • ISEPAMICINPTFDAG7K224460P
  • SCH21420CNNCI
  • 1-N-HAPA-gentamicin BSYNCI
  • IsepamicinPTNCI
DEFINITION
  • A broad-spectrum aminoglycoside antibiotic structurally related to gentamicin and amikacin. Isepamicin has activity similar to amikacin but with better activity against bacterial strains with resistance to other aminoglycosides, such as strains producing 6'-N-aminoglycoside acetyltransferase. Isepamicin is not metabolized and is excreted via the kidneys. This agent exerts a long postantibiotic effect allowing for once daily dosing.NCI
code
  • C83838
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