About: Deoxycytidine Analogue TAS-109     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Deoxycytidine Analogue TAS-109
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
  • Nucleic Acid, Nucleoside, or Nucleotide
Preferred_Name
  • Deoxycytidine Analogue TAS-109
NCI_META_CUI
  • CL388479
PDQ_Open_Trial_Search_ID
  • 633936
PDQ_Closed_Trial_Search_ID
  • 633936
Legacy_Concept_Name
  • Deoxycytidine_Analogue_TAS-109
FULL_SYN
  • TAS-109CNNCI
  • Deoxycytidine Analogue TAS-109PTNCI
DEFINITION
  • An analogue of the nucleoside deoxycytidine with potential antineoplastic activity. Nucleoside analogue TAS-109 is incorporated into DNA and directly inhibits the activity of DNA polymerase, which may result in inhibition of DNA replication and cell cycle arrest in the S and G2/M phases, DNA fragmentation, and tumor cell apoptosis.NCI
code
  • C82697
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