About: Tubulin Inhibitor ALB 109564(a)     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Tubulin Inhibitor ALB 109564(a)
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Tubulin Inhibitor ALB 109564(a)
UMLS_CUI
  • C2703136
PDQ_Open_Trial_Search_ID
  • 610130
PDQ_Closed_Trial_Search_ID
  • 610130
Legacy_Concept_Name
  • Tubulin_Inhibitor_ALB_109564_a
FULL_SYN
  • ALB 109564(a)CNNCI
  • Tubulin Inhibitor ALB 109564(a)PTNCI
  • 12'-methylthiovinblastine dihydrochlorideSNNCI
DEFINITION
  • A semi-synthetic derivative of the vinka alkaloid vinblastine with potential antineoplastic activity. Tubulin inhibitor ALB 109564(a) binds to tubulin monomers and inhibits microtubule formation, resulting in disruption of mitotic spindle assembly and arrest of tumor cells in the G2/M phase of the cell cycle.NCI
code
  • C78842
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