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AttributesValues
rdf:type
rdfs:label
  • Oxacillin Sodium Anhydrous
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Oxacillin Sodium Anhydrous
UMLS_CUI
  • C2698675
CAS_Registry
  • 1173-88-2
FDA_UNII_Code
  • 4TWD2995UP
Contributing_Source
  • FDA
Chemical_Formula
  • C19H18N3O5S.Na
Legacy_Concept_Name
  • Oxacillin_Sodium_Anhydrous
CHEBI_ID
  • CHEBI:52134
FULL_SYN
  • Oxacillin Sodium AnhydrousPTNCI
  • OXACILLIN SODIUM ANHYDROUSPTFDA4TWD2995UP
DEFINITION
  • The anhydrous form of the sodium salt of oxacillin, a semisynthetic penicillinase-resistant and acid-stable penicillin with antibacterial activity. Oxacillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.NCI
code
  • C76225
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