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AttributesValues
rdf:type
rdfs:label
  • Cefetecol
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Cefetecol
UMLS_CUI
  • C2699138
CAS_Registry
  • 127182-67-6
FDA_UNII_Code
  • ST0WR0R5X1
Contributing_Source
  • FDA
Chemical_Formula
  • C20H17N5O9S2.4H2O
Legacy_Concept_Name
  • Cefetecol
FULL_SYN
  • CEFETECOLPTFDAST0WR0R5X1
  • CefetecolPTNCI
DEFINITION
  • A broad-spectrum, fourth-generation cephalosporin with antibacterial activity. Cefetecol binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.NCI
code
  • C76165
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