About: Oxprenolol Hydrochloride     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Oxprenolol Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Oxprenolol Hydrochloride
UMLS_CUI
  • C0700460
CAS_Registry
  • 6452-73-9
FDA_UNII_Code
  • F4XSI7SNIU
Contributing_Source
  • FDA
Chemical_Formula
  • C15H23NO3.HCl
Legacy_Concept_Name
  • Oxprenolol_Hydrochloride
FULL_SYN
  • Oxprenolol HydrochloridePTNCI
  • OXPRENOLOL HYDROCHLORIDEPTFDAF4XSI7SNIU
DEFINITION
  • The hydrochloride salt form of oxprenolol, a lipophilic, nonselective beta-adrenergic receptor antagonist with anti-arrhythmic, anti-anginal and antihypertensive activities. Oxprenolol competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. In addition, oxprenolol prevents the release of renin, a hormone secreted by the kidneys that causes constriction of blood vessels.NCI
code
  • C66277
is Has_Salt_Form of
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