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AttributesValues
rdf:type
rdfs:label
  • Meluadrine
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Meluadrine
UMLS_CUI
  • C1881776
CAS_Registry
  • 134865-33-1
FDA_UNII_Code
  • FYC8314117
Contributing_Source
  • FDA
Chemical_Formula
  • C12H18ClNO2
Legacy_Concept_Name
  • Meluadrine
FULL_SYN
  • MELUADRINEPTFDAFYC8314117
  • MeluadrinePTNCI
DEFINITION
  • A beta-adrenergic receptor agonist with tocolytic activity. Meluadrine binds to and activates beta-2 adrenergic receptors of myometrial smooth muscle in the uterus, thereby activates adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels leads to a reduction in intracellular calcium concentration, thereby causes smooth muscle relaxation and decreases the intensity of uterine contractions.NCI
code
  • C66083
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