About: Hetacillin Potassium     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Hetacillin Potassium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Hetacillin Potassium
UMLS_CUI
  • C0812398
CAS_Registry
  • 5321-32-4
FDA_UNII_Code
  • 95PFX5932Y
Contributing_Source
  • FDA
Chemical_Formula
  • C19H22N3O4S.K
Legacy_Concept_Name
  • Hetacillin_Potassium
CHEBI_ID
  • CHEBI:34789
FULL_SYN
  • HETACILLIN POTASSIUMPTFDA95PFX5932Y
  • Hetacillin PotassiumPTNCI
DEFINITION
  • The potassium salt of hetacillin, a semi-synthetic penicillin antibiotic with bactericidal activity. Hetacillin is a prodrug that is converted to ampicillin via esterases. Ampicillin binds to and inactivated penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to an interruption of the bacterial cell wall and causes bacterial cell lysis.NCI
code
  • C65845
is Has_Salt_Form of
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