About: Butylscopolamine Bromide     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Butylscopolamine Bromide
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Butylscopolamine Bromide
UMLS_CUI
  • C0006519
CAS_Registry
  • 149-64-4
FDA_UNII_Code
  • 0GH9JX37C8
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 690309
PDQ_Closed_Trial_Search_ID
  • 690309
Chemical_Formula
  • C21H30NO4.Br
Legacy_Concept_Name
  • Butylscopolamine_Bromide
FULL_SYN
  • Butylscopolamine BromidePTNCI
  • Oral Hyoscine ButylbromideSYNCI
  • BUTYLSCOPOLAMINE BROMIDEPTFDA0GH9JX37C8
  • BuscopanSYNCI
DEFINITION
  • An orally available bromide salt form of butylscopolamine, a quaternary ammonium derivative of the alkaloid scopolamine, with anticholinergic property. Upon oral administration, hyoscine butylbromide binds to and blocks muscarinic receptors located on postganglionic parasympathetic nerve endings and on smooth muscle cells. This blocks the activity of acetylcholine (Ach) and causes its antispasmodic effect in the gastrointestinal (GI), urinary, uterine, and biliary tracts. This agent may also facilitate radiologic visualization of the GI tract.NCI
code
  • C65277
is Has_Salt_Form of
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