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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Ticarcillin Disodium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Ticarcillin Disodium
UMLS_CUI
  • C0546880
CAS_Registry
  • 4697-14-7
FDA_UNII_Code
  • G8TVV6DSYG
Contributing_Source
  • FDA
Chemical_Formula
  • C15H14N2O6S2.2Na
Legacy_Concept_Name
  • Ticarcillin_Disodium
CHEBI_ID
  • CHEBI:35017
FULL_SYN
  • TICARCILLIN DISODIUMPTFDAG8TVV6DSYG
  • TimentinBRNCI
  • Ticarcillin DisodiumPTNCI
DEFINITION
  • The disodium salt form of ticarcillin, a broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Similar to carbenicillin in action, ticarcillin inactivates the penicillin-sensitive transpeptidase C-terminal domain by opening the lactam ring. This inactivation prevents the cross-linkage of peptidoglycan strands, thereby inhibiting the third and last stage of bacterial cell wall synthesis. This leads to incomplete bacterial cell wall synthesis and eventually causes cell lysis.NCI
code
  • C65205
is Has_Salt_Form of
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