About: Glucuronic Acid     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Glucuronic Acid
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Chemical Viewed Structurally
Preferred_Name
  • Glucuronic Acid
UMLS_CUI
  • C0061444
CAS_Registry
  • 6556-12-3
FDA_UNII_Code
  • 8A5D83Q4RW
Contributing_Source
  • FDA
ALT_DEFINITION
  • A form of a type of sugar called glucose that helps remove harmful substances from the body. Glucuronic acid and the harmful substance combine in the liver and then are passed in the urine. Glucuronic acid is also found in other substances in the body, such as cartilage and synovial fluid (fluid found in the joints).NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 663166
PDQ_Closed_Trial_Search_ID
  • 663166
Chemical_Formula
  • C6H10O7
Legacy_Concept_Name
  • Glucuronic_Acid
CHEBI_ID
  • CHEBI:4178
  • CHEBI:47953
FULL_SYN
  • GLUCURONIC ACIDPTFDA8A5D83Q4RW
  • Glucuronic AcidPTNCI
  • glucuronic acidPTNCI-GLOSSCDR0000648598
DEFINITION
  • A carboxylic acid with structural similarity to glucose with detoxifying activity. The xenobiotic metabolism of various substances such as drugs, pollutants, bilirubin, androgens, estrogens, mineralocorticoids, glucocorticoids, fatty acid derivatives, retinoids, and bile acids involves glucuronidation, a process in which water-soluble, excretable glucuronides of these substances are formed via glycosidic linkages to glucuronic acid. UDP-glucuronic acid, formed in the liver through the linkage of glucuronic acid to uridine diphosphate (UDP) via a glycosidic bond, is an intermediate in the process of glucuronidation.NCI
code
  • C63810
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