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AttributesValues
rdf:type
rdfs:label
  • Levothyroxine
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Levothyroxine
UMLS_CUI
  • C1881373
CAS_Registry
  • 51-48-9
FDA_UNII_Code
  • Q51BO43MG4
Contributing_Source
  • FDA
Chemical_Formula
  • C15H11I4NO4
Legacy_Concept_Name
  • Levothyroxine
CHEBI_ID
  • CHEBI:18332
FULL_SYN
  • L-ThyroxineSYNCI
  • LEVOTHYROXINEPTFDAQ51BO43MG4
  • (-)-ThyroxineSYDTPNSC0036397
  • LevothyroxinePTNCI
DEFINITION
  • A synthetic levoisomer of thyroxine (T4), similar to the endogenous hormone produced by the thyroid gland. Thyroxine is de-iodinated to form triiodothyronine (T3) in the peripheral tissues. T3 enters the cell and binds to nuclear thyroid hormone receptors, and the hormone-receptor complex in turn triggers gene expression and produces proteins required in the regulation of cellular respiration, thermogenesis, cellular growth and differentiation, and metabolism of proteins, carbohydrates and lipids. T4 and T3 also possess cardiac stimulatory effect.NCI
code
  • C62080
is Has_Free_Acid_Or_Base_Form of
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