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AttributesValues
rdf:type
rdfs:label
  • Dyphylline
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Dyphylline
NSC_Code
  • 14305
UMLS_CUI
  • C0721457
CAS_Registry
  • 479-18-5
FDA_UNII_Code
  • 263T0E9RR9
Contributing_Source
  • FDA
Chemical_Formula
  • C10H14N4O4
Legacy_Concept_Name
  • Dyphylline
CHEBI_ID
  • CHEBI:4728
FULL_SYN
  • NeothyllineBRNCI
  • DiprophyllineSYNCI
  • DilorBRNCI
  • DylixBRNCI
  • DYPHYLLINEPTFDA263T0E9RR9
  • 1H-Purine-2,6-dione, 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethylSNNCI
  • LufyllinBRNCI
  • 7-(2,3-Dioxypropyl)theophyllineSNNCI
  • DyphyllinePTNCI
DEFINITION
  • A xanthine derivative. Dyphilline exerts bronchodilator effects and to a lesser extent vasodilator and diuretic properties. Dyphilline probably acts as a competitive inhibitor of phosphodiesterase which leads to an increase in intracellular cAMP. This results in relaxation of bronchial smooth muscle and other smooth muscles. Dyphylline may also antagonize adenosine receptors. Dyphylline is used in the treatment of acute bronchial asthma, chronic bronchitis and emphysema.NCI
code
  • C47504
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