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AttributesValues
rdf:type
rdfs:label
  • Protein Kinase B
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Enzyme
Preferred_Name
  • Protein Kinase B
UMLS_CUI
  • C0164786
ALT_DEFINITION
  • A group of enzymes involved in several processes related to cell growth and survival. Protein kinase B enzymes help to transfer signals inside cells. A protein kinase B enzyme is a type of serine/threonine protein kinase.NCI-GLOSS
Legacy_Concept_Name
  • Protein_Kinase_B
FULL_SYN
  • AktPTNCI-GLOSSCDR0000653105
  • AKTSYNCI
  • Protein Kinase BPTNCI
  • protein kinase BPTNCI-GLOSSCDR0000653106
DEFINITION
  • Expressed in diverse tissues, Protein Kinase B (AKT/RAC Family) is a group (Alpha, Beta and Gamma) of cytoplasmic serine/threonine enzymes that covalently transfer the terminal, gamma phosphate group from ATP to a variety of substrate proteins and regulate cell signaling responses to insulin, PDGF, and IGF1 (through PI3K) involved in cell survival, cell proliferation, differentiation, apoptosis, glycogen synthesis, and glucose uptake.NCI
code
  • C41625
is someValuesFrom of
is Has_Target of
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