About: Integrin aVBeta3

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Integrin aVBeta3
rdfs:subClassOf	Integrins nodeID://b682891 nodeID://b682892 nodeID://b682893 nodeID://b682894 nodeID://b682895 nodeID://b682896 nodeID://b682897
Semantic_Type	Amino Acid, Peptide, or Protein
Preferred_Name	Integrin aVBeta3
UMLS_CUI	C1138427
Legacy_Concept_Name	Integrin-aVBeta3
FULL_SYN	Integrin Alpha-V/Beta-3SYNCI aVBeta3 IntegrinSYNCI Integrin aVBeta3PTNCI aVBeta3SYNCI Integrin AlphaV/Beta3SYNCI
DEFINITION	Involved in cell adhesion and signaling, human Integrin-aVBeta3 is composed of type I membrane protein chains Integrin Alpha V (disulfide-linked heavy and light chains) and Integrin Beta 3 that recognize RGD sequences. Multiple heterodimeric alpha/beta combinations result in different integrins. aV/beta-3 is a receptor for cytotactin, fibronectin, laminin, MMP-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin, and von Willebrand factor. (NCI)NCI
code	C38953
is someValuesFrom of	nodeID://b659475 nodeID://b723088 nodeID://b723091
is Has_Target of	Etaracizumab Integrin Receptor Antagonist GLPG0187 Cilengitide

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