About: Pancreatic Proteolytic Enzymes     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Pancreatic Proteolytic Enzymes
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Enzyme
Preferred_Name
  • Pancreatic Proteolytic Enzymes
UMLS_CUI
  • C2825138
PDQ_Open_Trial_Search_ID
  • 43492
PDQ_Closed_Trial_Search_ID
  • 43492
Legacy_Concept_Name
  • Proteolytic_Enzymes
FULL_SYN
  • Pancreatic Proteolytic EnzymesPTNCI
  • Pancreatic Enzymes, ProteolyticSYNCI
DEFINITION
  • Enzymes produced and secreted by the pancreas which aid in the proteolysis of proteins in the digestive tract. Pancreatic proteolytic enzymes include trypsin, chymotrypsin and carboxypeptidase; these enzymes are secreted as zymogens, inactive precursors of the enzymes, and are activated in the lumen of the digestive canal. Another proteolytic enzyme, enteropeptidase, is associated with the brush border of enterocytes; this enzyme catalyses the conversion of trypsinogen into trypsin which, in turn, can activate a number of other pancreatic zymogens. (NCI04)NCI
code
  • C38728
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