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AttributesValues
rdf:type
rdfs:label
  • Carbenicillin
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Antibiotic
  • Organic Chemical
Preferred_Name
  • Carbenicillin
NSC_Code
  • 111071
UMLS_CUI
  • C0006976
CAS_Registry
  • 4697-36-3
FDA_UNII_Code
  • G42ZU72N5G
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 39174
PDQ_Closed_Trial_Search_ID
  • 39174
Chemical_Formula
  • C17H18N2O6S
Legacy_Concept_Name
  • Carbenicillin
CHEBI_ID
  • CHEBI:3393
FULL_SYN
  • CARBENICILLINPTFDAG42ZU72N5G
  • CARBENICILLINSYDTPNSC0111071
  • CarbenicillinPTNCI
  • GeopenSYDTPNSC0111071
  • PyopenSYDTPNSC0111071
  • GeopenBRNCI
  • PyopenFBNCI
DEFINITION
  • A broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Carbenicillin acylates the penicillin-sensitive transpeptidase C-terminal domain by opening the lactam ring. This inactivation prevents the cross-linkage of peptidoglycan strands, thereby inhibiting the third and last stage of bacterial cell wall synthesis. This leads to incomplete bacterial cell wall synthesis and eventually causes cell lysis.NCI
code
  • C343
is Has_Free_Acid_Or_Base_Form of
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