About: Neuromedin U     Goto   Sponge   Distinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Neuromedin U
equivalentClass
OMIM_Number
  • 605103
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Hormone
Preferred_Name
  • Neuromedin U
UMLS_CUI
  • C0068606
Legacy_Concept_Name
  • Neuromedin-U_Protein
FULL_SYN
  • Neuromedin UPTNCI
  • NMUSYNCI
  • Neuromedin U-25SYNCI
  • NMU-25SYNCI
Swiss_Prot
  • P48645
DEFINITION
  • Expressed throughout the enteric and central nervous systems by human NMU Gene (NMU Family), 174-aa 20-kDa (precursor) secreted Neuromedin U (25-aa) is a potent neuropeptide ligand of G Protein-Coupled Receptor 66 and Neuromedin U Receptor 2 (a GPCR) that stimulates smooth muscle contractions of the ileum, urinary bladder, and uterus, increases blood pressure, alters ion transport in the gut, controls local blood flow, and regulates adrenocortical function. The precursor contains a signal peptide and 4 paired basic residues, putative proteolytic processing sites, indicating that the precursor may generate 3 peptides, including NMU located near the C terminus. (NCI)NCI
code
  • C33975
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