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AttributesValues
rdf:type
rdfs:label
  • Azlocillin
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Antibiotic
  • Organic Chemical
Preferred_Name
  • Azlocillin
UMLS_CUI
  • C0004499
CAS_Registry
  • 37091-66-0
FDA_UNII_Code
  • HUM6H389W0
Contributing_Source
  • FDA
ALT_DEFINITION
  • A semisynthetic ampicillin-derived acylureido penicillin.MSH2002_06_01
PDQ_Open_Trial_Search_ID
  • 39160
PDQ_Closed_Trial_Search_ID
  • 39160
Chemical_Formula
  • C20H23N5O6S
Legacy_Concept_Name
  • Azlocillin
CHEBI_ID
  • CHEBI:2956
FULL_SYN
  • AzlinBRNCI
  • AZLOCILLINPTFDAHUM6H389W0
  • AzlocillinPTNCI
DEFINITION
  • A semisynthetic, extended spectrum acylampicillin with antibacterial activity. Azlocillin binds to penicillin-binding proteins (PBPs) located inside the bacterial cell wall, thereby inhibiting the cross-linking of peptidoglycans, which are critical components of the bacterial cell wall. This prevents proper bacterial cell wall synthesis, thereby results in the weakening of the bacterial cell wall and eventually leading to cell lysis.NCI
code
  • C293
is Has_Free_Acid_Or_Base_Form of
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