About: Mitotic Sister Chromatid Cohesion     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Mitotic Sister Chromatid Cohesion
rdfs:subClassOf
Semantic_Type
  • Cell Function
Preferred_Name
  • Mitotic Sister Chromatid Cohesion
UMLS_CUI
  • C1516543
Legacy_Concept_Name
  • Chromosome_Cohesion
FULL_SYN
  • Mitotic Sister Chromatid CohesionPTNCI
  • Chromosome CohesionSYNCI
DEFINITION
  • The faithful segregation of genetic information requires highly orchestrated changes of chromosome structure during the mitotic cell cycle. The linkage between duplicated sister DNAs is established during S phase and maintained throughout G2 phase (cohesion). In early mitosis, dramatic structural changes occur to produce metaphase chromosomes, each consisting of a pair of compacted sister chromatids (condensation). At anaphase onset, a signal is produced to disrupt the linkage between sister chromatids (separation), allowing them to be pulled apart to opposite poles of the cell. (from PubMed 10966455)NCI
code
  • C28752
is someValuesFrom of
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