About: Hippocalcin     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Hippocalcin
equivalentClass
OMIM_Number
  • 142622
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • Hippocalcin
UMLS_CUI
  • C1505568
Legacy_Concept_Name
  • Hippocalcin
FULL_SYN
  • HippocalcinPTNCI
  • HPCA ProteinSYNCI
  • HPCASYNCI
  • p23KSYNCI
  • BDR-2SYNCI
  • Neuron Specific Calcium Binding Protein HippocalcinSYNCI
Swiss_Prot
  • P32076
DEFINITION
  • Encoded by human HPCA Gene (Recoverin Subfamily), 192-amino acid 22-kD neuron-specific Hippocalcin is myristoylated, plasma membrane-associated, binds two Ca(2+) ions, and contains the EF-hand Ca(2+)-binding motif. Human amino acid sequence shows complete identity (and 92% nucleotide identity) with rat; it is also identical to mouse hippocalcin. Hippocalcin shows striking similarity to photoreceptor Ca(2+)-sensitive proteins that regulate photosignal transduction. Displaying recoverin activity and a Ca(2+)-dependent inhibition of rhodopsin kinase, it may be involved in the Ca(2+)-dependent regulation of rhodopsin phosphorylation. (from LocusLink, Swiss-Prot, OMIM, and NCI)NCI
code
  • C26356
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