About: Cullin Family Gene     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Cullin Family Gene
rdfs:subClassOf
Semantic_Type
  • Gene or Genome
Preferred_Name
  • Cullin Family Gene
UMLS_CUI
  • C1333167
Legacy_Concept_Name
  • Cullin_Family_Gene
FULL_SYN
  • Cullin Family GenePTNCI
Gene_Encodes_Product
  • Cullin Family Protein
DEFINITION
  • Cullin Family Genes encode Cullin Family Proteins, which are components of SCF ubiquitin ligase complexes or E3 ubiquitin ligase complexes with elongin BC complexes and other factors, involved in ubiquitination and proteasomal degradation of target cell cycle, signal transduction, and transcription proteins. Cullins may act in these multisubunit complexes as a scaffold for substrates and ubiquitin-conjugating enzymes and interact with RBX1, RNF7, CYCE, and/or TIP120A/CAND1. (NCI)NCI
code
  • C26074
is rdfs:subClassOf of
is someValuesFrom of
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