About: Interleukin-2 Liposome     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Interleukin-2 Liposome
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Immunologic Factor
Preferred_Name
  • Interleukin-2 Liposome
UMLS_CUI
  • C0281031
In_Clinical_Trial_For
  • Refractory Cancer and Stage III Malignant Melanoma.
PDQ_Open_Trial_Search_ID
  • 41486
PDQ_Closed_Trial_Search_ID
  • 41486
Legacy_Concept_Name
  • Interleukin-2_Liposome
FULL_SYN
  • Interleukin-2 LiposomePTNCI
  • Liposome encapsulated interleukin-2SYNCI
DEFINITION
  • A formulation in which liposomes are loaded with the cytokine interleukin-2 (IL-2). By activating cytotoxic T-lymphocytes, such as lymphokine-activated killer cells, and increasing levels of the cytotoxic cytokines interferon-gamma (IFN-gamma) and transforming growth factor-beta (TGF-beta), IL-2 may exhibit antitumoral activity. Liposomal formulations of IL-2 may promote entry of the cytokine into target tumor cells and may be used as an immunoadjuvant in cancer vaccine therapy. (NCI04)NCI
code
  • C2373
is someValuesFrom of
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