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AttributesValues
rdf:type
rdfs:label
  • Neuregulin
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Biologically Active Substance
Preferred_Name
  • Neuregulin
UMLS_CUI
  • C0752253
Legacy_Concept_Name
  • Neuregulin
FULL_SYN
  • Sensory-and-motor-derived factorSYNCI
  • NDFABNCI
  • GGFSYNCI
  • Neu-Differentiation FactorSYNCI
  • ARIASYNCI
  • Glial Growth FactorSYNCI
  • HeregulinSYNCI
  • NeuregulinPTNCI
DEFINITION
  • Neuregulin (heregulin) polypeptides have been shown to interact with and activate the ErbB2, ErbB3 and ErbB4 receptor proteins, and have been found to be essential for the normal development of the cardiovascular, pancreatic and nervous systems. Neuregulins are involved in the normal development of mammary gland, are secreted by breast cancer cells, and can alternatively promote or inhibit breast cancer cell division.NCI
code
  • C20433
is rdf:first of
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