About: 5-Fluorouridine     Goto   Sponge   Distinct   Permalink

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http://linked.open...gbank/description
  • 5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. This compound belongs to the pyrimidine nucleosides and analogues. These are compounds comprising a pyrimidine base attached to a sugar. 5-fluorouridine is known to target uridine phosphorylase. FUrd is often used in chemical and biochemical comparison studies with fluorouracil and thymine analogs. (en)
http://linked.open...generalReferences
  • # Miracco EJ, Mueller EG: The products of 5-fluorouridine by the action of the pseudouridine synthase TruB disfavor one mechanism and suggest another. J Am Chem Soc. 2011 Aug 10;133(31):11826-9. doi: 10.1021/ja201179f. Epub 2011 Jul 15. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/21744792 # Arbos P, Campanero MA, Irache JM: RP-LC determination of 5-fluorouridine in nanoparticulate formulations. J Pharm Biomed Anal. 2002 Jun 1;28(5):857-66. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/12039627 (en)
http://linked.open...gy/drugbank/group
  • experimental (en)
sameAs
Title
  • 5-Fluorouridine (en)
adms:identifier
http://linked.open.../drugbank/synonym
  • 5-Fluoro-uridine (en)
  • 5-Fluorouracil 1beta-D-ribofuranoside (en)
  • 5-Fur (en)
  • FUrd (en)
http://linked.open...ynthesisReference
  • Setsuro Fujii, Eiichi Sakakibara, "2'-Deoxy-5-fluorouridine derivative and a process for producing the same and an antitumor agent comprising the same." U.S. Patent US4490366, issued October, 1977. (en)
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http://linked.open...nk/Polarizability
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http://linked.open...atable-Bond-Count
http://linked.open...casRegistryNumber
  • 316-46-1 (en)
http://linked.open...k/Bioavailability
http://linked.open...bank/Ghose-Filter
http://linked.open...nk/MDDR-Like-Rule
http://linked.open...ank/Melting-Point
http://linked.open...k/Number-of-Rings
http://linked.open...siological-Charge
http://linked.open...bank/Rule-of-Five
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http://linked.open...-strongest-basic-
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