About: Cyclopentolate     Goto   Sponge   Distinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
http://linked.open...gbank/description
  • A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia. [PubChem] (en)
http://linked.open...y/drugbank/dosage
http://linked.open...generalReferences
  • # "Link":http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202173.html (en)
http://linked.open...gy/drugbank/group
  • approved (en)
http://linked.open...ugbank/indication
  • Used mainly to produce mydriasis and cycloplegia for diagnostic purposes. (en)
http://linked.open...bank/manufacturer
sameAs
Title
  • Cyclopentolate (en)
adms:identifier
http://linked.open...mechanismOfAction
  • By blocking muscarinic receptors, cyclopentolate produces dilatation of the pupil (mydriasis) and prevents the eye from accommodating for near vision (cycloplegia). (en)
http://linked.open...drugbank/packager
http://linked.open.../drugbank/synonym
  • Cyclopentolate (en)
  • (+-)-Cyclopentolate (en)
  • (±)-cyclopentolate (en)
  • 2-(dimethylamino)Ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate (en)
  • Ciclopentolato (en)
  • Cyclopentolatum (en)
  • 1-Hydroxy-alpha-phenylcyclopentaneacetic acid 2-(dimethylamino)ethyl ester (en)
  • beta-(dimethylamino)Ethyl (1-hydroxycyclopentyl)phenylacetate (en)
  • 2-Phenyl-2-(1-hydroxycyclopentyl)ethanoic acid beta-(dimethylamino)ethyl ester (en)
  • α-(1-hydroxycyclopentyl)benzeneacetic acid 2-(dimethylamino)ethyl ester (en)
  • β-dimethylaminoethyl (1-hydroxycyclopentyl)phenylacetate (en)
  • beta-Dimethylaminoethyl (1-hydroxycyclopentyl)phenylacetate (en)
  • 2-(dimethylamino)Ethyl 1-hydroxy-alpha-phenylcyclopentaneacetate (en)
  • alpha-(1-Hydroxycyclopentyl)benzeneacetic acid 2-(dimethylamino)ethyl ester (en)
http://linked.open...drugbank/toxicity
  • Oral LD<sub>50</sub> in the rat is 4000 mg/kg and 960 mg/kg in the mouse. Symptoms of overdose include tachycardia, dizziness, dry mouth, behavioral disturbances, uncoordination and drowsiness. (en)
http://linked.open.../drug/hasAHFSCode
http://linked.open.../drugbank/mixture
http://linked.open...ogy/drugbank/salt
  • (en)
http://linked.open...ynthesisReference
  • Treves, G.R.; US. Patent 2,554,511; May 29,1951; assigned to Schieffelin & Co. (en)
foaf:page
http://linked.open...ugbank/IUPAC-Name
http://linked.open...gy/drugbank/InChI
http://linked.open...Molecular-Formula
http://linked.open.../Molecular-Weight
http://linked.open...noisotopic-Weight
http://linked.open...y/drugbank/SMILES
http://linked.open.../Water-Solubility
http://linked.open...ogy/drugbank/logP
http://linked.open...ogy/drugbank/logS
http://linked.open...l/drug/hasATCCode
http://linked.open...nd-Acceptor-Count
http://linked.open...-Bond-Donor-Count
http://linked.open...drugbank/InChIKey
http://linked.open...urface-Area--PSA-
http://linked.open...nk/Polarizability
http://linked.open...bank/Refractivity
http://linked.open...atable-Bond-Count
http://linked.open...ugbank/absorption
  • Absorbed following ophthalmic administration. (en)
http://linked.open.../affectedOrganism
  • Humans and other mammals (en)
http://linked.open...casRegistryNumber
  • 512-15-2 (en)
http://linked.open...drugbank/category
  • (en)
http://linked.open...gbank/containedIn
http://linked.open...k/Bioavailability
http://linked.open...bank/Ghose-Filter
http://linked.open...nk/MDDR-Like-Rule
http://linked.open...ank/Melting-Point
http://linked.open...k/Number-of-Rings
http://linked.open...siological-Charge
http://linked.open...bank/Rule-of-Five
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