About: Carboprost Tromethamine

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About: Carboprost Tromethamine Goto Sponge Distinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	A nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy. [PubChem] (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B4C6C-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4C6D-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4C6E-363D-11E5-9242-09173F13E4C5
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...ugbank/indication	For aborting pregnancy between the 13th and 20th weeks of gestation as calculated from the first day of the last normal menstrual period and in the following conditions related to second trimester abortion: 1. Failure of expulsion of the fetus during the course of treatment by another method; 2. Premature rupture of membranes in intrauterine methods with loss of drug and insufficient or absent uterine activity; 3. Requirement of a repeat intrauterine instillation of drug for expulsion of the fetus; 4. Inadvertent or spontaneous rupture of membranes in the presence of a previable fetus and absence of adequate activity for expulsion. Also for the treatment of postpartum hemorrhage due to uterine atony which has not responded to conventional methods of management. (en)
http://linked.open...bank/manufacturer	Par Pharmaceuticals Hospira inc
sameAs	Carboprost Tromethamine
Title	Carboprost Tromethamine (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00429/identifier/chebi/3404 http://linked.opendata.cz/resource/drugbank/drug/DB00429/identifier/drugbank/DB00429 http://linked.opendata.cz/resource/drugbank/drug/DB00429/identifier/kegg-drug/D00682 http://linked.opendata.cz/resource/drugbank/drug/DB00429/identifier/national-drug-code-directory/0009-0856-05 http://linked.opendata.cz/resource/drugbank/drug/DB00429/identifier/pharmgkb/PA164754883
http://linked.open...mechanismOfAction	Carboprost is a synthetic prostaglandin. It binds the prostaglandin E2 receptor, causing myometrial contractions, casuing the induction of labour or the expulsion of the placenta. Prostaglandins occur naturally in the body and act at several sites in the body including the womb (uterus). They act on the muscles of the womb, causing them to contract. (en)
http://linked.open...drugbank/packager	Hospira Inc. Luitpold pharmaceuticals inc
http://linked.open.../drugbank/synonym	Carboprost (en) (15S)-15-Methyl-pgf2alpha tromethamine salt (en) (15S)-15-Methylprostaglandin F2alpha tromethamine (en) 15(S)-15-Methyl-pgf2alpha tromethamine salt (en) 15(S)-15-Methylprostaglandin F2alpha tromethamine (en) Carboprost trometamol (en) 1,3-Dihydroxy-2-(hydroxymethyl)propan-2-aminium (5Z,9alpha,11beta,13e,15S)-9,11,15-trihydroxy-15-methylprosta-5,13-dien-1-oate (en) Methyldinoprost (en)
http://linked.open...drugbank/toxicity	Symptoms of overdose include irritation, nausea, vomiting, diarrhea, coughing, dyspnea, asthma, hypertension, flushing, and pyrexia. (en)
http://linked.open.../drug/hasAHFSCode	http://linked.opendata.cz/resource/AHFS/76-00-00
http://linked.open...ynthesisReference	Ming Li, "CRYSTALS OF CARBOPROST TROMETHAMINE AND THE PREPARATION METHOD AS WELL AS THE USES THEREOF." U.S. Patent US20130190404, issued July 25, 2013. (en)
foaf:page	http://www.drugs.com/mtm/carboprost.html http://www.rxlist.com/cgi/generic/hemabate.htm
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http://linked.open...Molecular-Formula	http://linked.opendata.cz/resource/drugbank/property/271B4C78-363D-11E5-9242-09173F13E4C5
http://linked.open.../Molecular-Weight	http://linked.opendata.cz/resource/drugbank/property/271B4C75-363D-11E5-9242-09173F13E4C5
http://linked.open...noisotopic-Weight	http://linked.opendata.cz/resource/drugbank/property/271B4C76-363D-11E5-9242-09173F13E4C5
http://linked.open...y/drugbank/SMILES	http://linked.opendata.cz/resource/drugbank/property/271B4C77-363D-11E5-9242-09173F13E4C5
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http://linked.open...l/drug/hasATCCode	Carboprost
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http://linked.open...bank/Refractivity	http://linked.opendata.cz/resource/drugbank/property/271B4C7C-363D-11E5-9242-09173F13E4C5
http://linked.open...atable-Bond-Count	http://linked.opendata.cz/resource/drugbank/property/271B4C7E-363D-11E5-9242-09173F13E4C5
http://linked.open.../affectedOrganism	Humans and other mammals (en)
http://linked.open...casRegistryNumber	58551-69-2 (en)
http://linked.open...gbank/containedIn	Hemabate 250 mcg/ml ampul Morphine Lp Epidural 0.5 mg/ml
http://linked.open...k/Bioavailability	http://linked.opendata.cz/resource/drugbank/property/271B4C85-363D-11E5-9242-09173F13E4C5
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http://linked.open...tional-IUPAC-Name	http://linked.opendata.cz/resource/drugbank/property/271B4C74-363D-11E5-9242-09173F13E4C5
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