About: Medrysone     Goto   Sponge   Distinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

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http://linked.open...gbank/description
  • Medrysone is a corticosteroid used in ophthalmology. [Wikipedia] (en)
http://linked.open...gy/drugbank/group
  • approved (en)
http://linked.open...ugbank/indication
  • For the treatment of allergic conjunctivitis, vernal conjunctivitis, episcleritis, and epinephrine sensitivity. (en)
http://linked.open...bank/manufacturer
sameAs
Title
  • Medrysone (en)
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http://linked.open...mechanismOfAction
  • There is no generally accepted explanation for the mechanism of action of ocular corticosteroids. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2. Initially, the drug binds to the glucocorticoid receptor in the cytosol. This migrates to the nucleus and binds to genetic elements which cause activation and repression of the involved genes in the inflammatory pathway. (en)
http://linked.open.../drugbank/synonym
  • HMS (en)
  • 11beta-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione (en)
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foaf:page
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  • Rapidly absorbed following oral administration. (en)
http://linked.open.../affectedOrganism
  • Humans and other mammals (en)
http://linked.open...casRegistryNumber
  • 2668-66-8 (en)
http://linked.open...drugbank/category
  • (en)
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