About: Capromab

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About: Capromab Goto Sponge Distinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	Capromab is a Murine IgG1 monoclonal 7E11-C5.3 antibody that recognizes prostate specific membrane antigen (PSMA – also known as glutamate carboxypeptidase 2) from prostate cancer cells and normal prostate tissue. It is linked to pendetide, a derivative of DTPA. Pendetide acts as a chelating agent for the radionuclide indium-111. Capromab is used to image the extent of prostate cancer. (en)
http://linked.open...generalReferences	# http://www.google.com/patents/WO2013006706A1?cl=en # http://www.lens.org/lens/patent/US_4671958_A # http://www.google.ca/patents/US4741900 # http://www.google.com/patents/US5162504 (en)
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...ugbank/indication	For diagnosis of prostate cancer and detection of intra-pelvic metastases. (en)
sameAs	Capromab
Title	Capromab (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00089/identifier/drugbank/DB00089 http://linked.opendata.cz/resource/drugbank/drug/DB00089/identifier/national-drug-code-directory/57902-817-01 http://linked.opendata.cz/resource/drugbank/drug/DB00089/identifier/pharmgkb/PA164745489 http://linked.opendata.cz/resource/drugbank/drug/DB00089/identifier/wikipedia/Capromab
http://linked.open...mechanismOfAction	Binds selectively to cell-surface prostate-specific membrane antigen (PSMA) expressed on prostate tissues and tumors. (en)
http://linked.open...drugbank/packager	Astrazeneca pharmaceuticals lp
http://linked.open...outeOfElimination	Approximately 10% of the administered radioisotope dose is excreted in the urine during the 72 hours following intravenous infusion. (en)
http://linked.open.../drugbank/synonym	Capromab pendetide (en) In 111 Capromab pendetide (en)
http://linked.open...umeOfDistribution	* 4 ± 2.1 L (en)
http://linked.open.../affectedOrganism	Humans and other mammals (en)
http://linked.open...casRegistryNumber	145464-28-4 (en)
http://linked.open...drugbank/category	(en)
http://linked.open...rugbank/clearance	* 42 +/- 22 mL/hr (en)
http://linked.open...gbank/containedIn	Prostascint kit
http://linked.open...ank/Melting-Point	http://linked.opendata.cz/resource/drugbank/property/271B4434-363D-11E5-9242-09173F13E4C5

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