"Leo 1031SYDTPNSC0171345" . . "134087"^^ . "PREDNIMUSTINEPTFDA9403SIO2S8" . "9403SIO2S8"^^ . "Prednimustine"^^ . . "39560"^^ . "39560"^^ . . "C768"^^ . "Chlorambucil Prednisolone EsterSYNCI" . "Pharmacologic Substance"^^ . . "The prednisolone ester of chlorambucil and nitrogen mustard alkylating agent with antineoplastic activity. Prednimustine itself is not cytotoxic, however, it becomes cytotoxic upon hydrolysis by serum esterases to chlorambucil. Therefore, the increased potency of prednimustine is linked to the prolonged availability of free chlorambucil.NCI" . "Prednimustine"^^ . "SterecytSYDTPNSC0171345" . "Prednimustine"^^ . "C35H45Cl2NO6"^^ . "PrednimustineSYDTPNSC0171345" . "FDA"^^ . "11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-[4-[p-[bis(3-chloroethyl)amino]phenyl]butyrate]SNNCI" . "C0032949"^^ . "(11beta-21-[4-[4-[bis(2-chloroethyl)amino]phenyl]-1-oxobutoxy]-11,17-dihydroxypregna-1,4-diene-3,20-dioneSNNCI" . "Steroid"^^ . "SterecytFBNCI" . . "PrednimustinePTNCI" . "StereocytFBNCI" . "171345"^^ . "LEO-1031CNNCI" . "Ester of CHLORAMBUCIL and PREDNISOLONE used as a combination alkylating agent and synthetic steroid to treat various leukemias and other neoplasms. It causes gastrointestinal and bone marrow toxicity.MSH2002_06_01" . "29069-24-7"^^ .