<http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>Nipent</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI-GLOSS</n0:term-source><n0:source-code>CDR0000618582</n0:source-code></n0:ComplexTerm>" . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>pentostatin</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI-GLOSS</n0:term-source><n0:source-code>CDR0000045190</n0:source-code></n0:ComplexTerm>" . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#A8> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>2'-Deoxycoformycin</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>" . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://www.w3.org/2002/07/owl#equivalentClass> _:vb636980 . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>PENTOSTATIN</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>FDA</n0:term-source><n0:source-code>395575MZO7</n0:source-code></n0:ComplexTerm>" . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>Covidarabine</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>DTP</n0:term-source><n0:source-code>NSC0218321</n0:source-code></n0:ComplexTerm>" . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>CI-825</n0:term-name><n0:term-group>CN</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>" . _:vb702266 <http://www.w3.org/2002/07/owl#onProperty> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#R146> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>Deoxycoformycin</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>" . _:vb636980 <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.w3.org/2002/07/owl#Class> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P106> "Nucleic Acid, Nucleoside, or Nucleotide"^^<http://www.w3.org/2001/XMLSchema#string> . _:vb780408 <http://www.w3.org/1999/02/22-rdf-syntax-ns#rest> <http://www.w3.org/1999/02/22-rdf-syntax-ns#nil> . _:vb780408 <http://www.w3.org/1999/02/22-rdf-syntax-ns#first> _:vb702268 . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P108> "Pentostatin"^^<http://www.w3.org/2001/XMLSchema#string> . _:vb702265 <http://www.w3.org/2002/07/owl#someValuesFrom> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12535> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>Nipent</n0:term-name><n0:term-group>BR</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>" . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P350> "C11H16N4O4"^^<http://www.w3.org/2001/XMLSchema#string> . _:vb702267 <http://www.w3.org/2002/07/owl#someValuesFrom> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40577> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P330> "39210"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P210> "63677-95-2"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P207> "C0030896"^^<http://www.w3.org/2001/XMLSchema#string> . _:vb702267 <http://www.w3.org/2002/07/owl#onProperty> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#R124> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P322> "FDA"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>Pentostatine</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>" . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>2'-Deoxycoformycin</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>DTP</n0:term-source><n0:source-code>NSC0247520</n0:source-code></n0:ComplexTerm>" . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://www.w3.org/2002/07/owl#sameAs> <http://linked.opendata.cz/resource/ndfrt/ingredient/N0000007243> . _:vb780405 <http://www.w3.org/1999/02/22-rdf-syntax-ns#first> _:vb702265 . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P329> "39210"^^<http://www.w3.org/2001/XMLSchema#string> . _:vb728099 <http://www.w3.org/1999/02/22-rdf-syntax-ns#rest> _:vb780405 . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P106> "Antibiotic"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://linked.opendata.cz/ontology/mesh/hasConcept> <http://linked.opendata.cz/resource/mesh/concept/M0023987> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P175> "218321"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>(R)-3-(2-Deoxy-.beta.-D-erythro-pentofuranosyl)-3,6,7, 8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>DTP</n0:term-source><n0:source-code>NSC0247520</n0:source-code></n0:ComplexTerm>" . _:vb780407 <http://www.w3.org/1999/02/22-rdf-syntax-ns#first> _:vb702267 . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P303> "Chronic lymphocytic leukemia; Graft versus Host disease; Lymphoid malignancies; Non-Hodgkins lymphoma; Renal cell cancer"^^<http://www.w3.org/2001/XMLSchema#string> . _:vb780406 <http://www.w3.org/1999/02/22-rdf-syntax-ns#first> _:vb702266 . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P175> "247520"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>Covidarabine</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>" . _:vb780407 <http://www.w3.org/1999/02/22-rdf-syntax-ns#rest> _:vb780408 . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://www.w3.org/2000/01/rdf-schema#label> "Pentostatin"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P325> "<n0:ComplexDefinition xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:def-definition>The active ingredient in a drug that is used to treat hairy cell leukemia and is being studied in the treatment of other types of cancer. Pentostatin blocks a protein needed for cell growth and may kill cancer cells. It is made by a bacterium. It is a type of adenosine deaminase inhibitor.</n0:def-definition><n0:def-source>NCI-GLOSS</n0:def-source></n0:ComplexDefinition>" . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>PENTOSTATIN</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>DTP</n0:term-source><n0:source-code>NSC0247520</n0:source-code></n0:ComplexTerm>" . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P210> "53910-25-1"^^<http://www.w3.org/2001/XMLSchema#string> . _:vb702266 <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.w3.org/2002/07/owl#Restriction> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>DCF</n0:term-name><n0:term-group>AB</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>" . _:vb780405 <http://www.w3.org/1999/02/22-rdf-syntax-ns#rest> _:vb780406 . _:vb702267 <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.w3.org/2002/07/owl#Restriction> . _:vb636980 <http://www.w3.org/2002/07/owl#intersectionOf> _:vb728099 . _:vb702268 <http://www.w3.org/2002/07/owl#someValuesFrom> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C41621> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>PD-81565</n0:term-name><n0:term-group>CN</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>" . _:vb702265 <http://www.w3.org/2002/07/owl#onProperty> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#R72> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>(R)-3-(2-Deoxy-beta-D-erythro-pentofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol</n0:term-name><n0:term-group>SN</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>" . _:vb780406 <http://www.w3.org/1999/02/22-rdf-syntax-ns#rest> _:vb780407 . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#code> "C732"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>Co-Vidarabine</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>" . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P366> "Pentostatin"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>Co-vidarabine</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>DTP</n0:term-source><n0:source-code>NSC0247520</n0:source-code></n0:ComplexTerm>" . _:vb702265 <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.w3.org/2002/07/owl#Restriction> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://www.w3.org/2002/07/owl#sameAs> <http://linked.opendata.cz/resource/fda-spl/ingredient/395575MZO7> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P97> "<n0:ComplexDefinition xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:def-definition>A purine nucleotide analogue antibiotic isolated from the bacterium Streptomyces antibioticus. Also known as 2'-deoxycoformycin, pentostatin binds to and inhibits adenine deaminase (ADA), an enzyme essential to purine metabolism; ADA activity is greatest in cells of the lymphoid system with T-cells having higher activity than B-cells and T-cell malignancies higher ADA activity than B-cell malignancies. Pentostatin inhibition of ADA appears to result in elevated intracellular levels of dATP which may block DNA synthesis through the inhibition of ribonucleotide reductase. This agent may also inhibit RNA synthesis and may selectively deplete CD26+ lymphocytes. (NCI04)</n0:def-definition><n0:def-source>NCI</n0:def-source></n0:ComplexDefinition>" . _:vb702268 <http://www.w3.org/2002/07/owl#onProperty> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#R125> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.w3.org/2002/07/owl#Class> . _:vb728099 <http://www.w3.org/1999/02/22-rdf-syntax-ns#first> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2157> . _:vb702266 <http://www.w3.org/2002/07/owl#someValuesFrom> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16261> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P319> "395575MZO7"^^<http://www.w3.org/2001/XMLSchema#string> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90> "<n0:ComplexTerm xmlns:n0=\"http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#\"><n0:term-name>Pentostatin</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>" . _:vb702268 <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.w3.org/2002/07/owl#Restriction> . <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C732> <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P302> "Chronic lymphocytic leukemia; Cutaneous t-cell lymphoma; Hairy cell leukemia"^^<http://www.w3.org/2001/XMLSchema#string> .