"C0022020"^^ . "A polyether antibiotic isolated from Streptomyces conglobatus sp. nov. Trejo with antineoplastic activity. Ionomycin is a calcium ionophore that increases intracellular Ca++ levels, possibly relating to endonuclease activation of lymphocytes and decreased ratio of Bcl-2 to Bax and ultimately apoptosis. In addition, this agent is used to investigate the role of intracellular calcium in cellular processes. (NCI)NCI" . . "ionomycinPTNCI-GLOSSCDR0000045998" . "Ionomycin"^^ . "Ionomycin"^^ . _:vb684339 . "Antibiotic"^^ . . . "Ionomycin"^^ . _:vb684339 . "56092-81-0"^^ . "C596"^^ . "CHEBI:63954"^^ . _:vb684339 . "43046"^^ . "43046"^^ . . _:vb684339 . "IonomycinPTNCI" .