"Glioblastoma"^^ . _:vb763761 _:vb676956 . _:vb676956 . _:vb763775 _:vb676970 . _:vb763772 _:vb676967 . _:vb763762 _:vb676957 . _:vb763763 _:vb676958 . "9440/3"^^ . _:vb676962 . _:vb763763 _:vb763764 . "Malignant"^^ . _:vb763774 _:vb676969 . _:vb763762 _:vb763763 . _:vb676963 . "Glioblastoma multiformePTCTEP10018337" . _:vb763767 _:vb763768 . _:vb676969 . _:vb763764 _:vb763765 . _:vb676971 . "Spongioblastoma MultiformeSYNCI" . _:vb676960 . _:vb763765 _:vb763766 . _:vb676968 . "glioblastoma multiformePTNCI-GLOSSCDR0000045699" . _:vb676961 . _:vb676963 . . _:vb676964 . _:vb763766 _:vb763767 . _:vb676966 . _:vb633215 _:vb730461 . _:vb763767 _:vb676962 . _:vb676967 . _:vb676957 . _:vb676964 . "grade IV astrocytomaPTNCI-GLOSSCDR0000044407" . "GBM (Glioblastoma)SYNCI" . _:vb676958 . _:vb763766 _:vb676961 . _:vb730461 . _:vb763776 _:vb676971 . _:vb676965 . _:vb763777 _:vb676972 . _:vb763765 _:vb676960 . "GlioblastomaSYNCITCGA" . _:vb676960 . _:vb676966 . _:vb763776 _:vb763777 . _:vb730461 _:vb730454 . _:vb633215 . _:vb676958 . _:vb676959 . _:vb676956 . _:vb676959 . _:vb676958 . _:vb676956 . "glioblastomaPTNCI-GLOSSCDR0000045698" . _:vb676957 . "Glioblastoma"^^ . "Grade IV Astrocytic TumorSYNCI" . _:vb676957 . _:vb676962 . . "A fast-growing type of central nervous system tumor that forms from glial (supportive) tissue of the brain and spinal cord and has cells that look very different from normal cells. GBM usually occurs in adults and affects the brain more often than the spinal cord.NCI-GLOSS" . _:vb763775 _:vb763776 . _:vb676972 . _:vb676961 . _:vb633215 . "C0017636"^^ . _:vb763777 . . _:vb676963 . _:vb676962 . _:vb676961 . _:vb676960 . _:vb676966 . _:vb676967 . _:vb676959 . _:vb676964 . _:vb763771 _:vb763772 . _:vb676970 . "Glioblastoma MultiformeSYNCI" . "Neoplastic Process"^^ . _:vb763770 _:vb763771 . _:vb676965 . _:vb763769 _:vb763770 . "CTEP"^^ . _:vb676970 . _:vb763768 _:vb763769 . _:vb676970 . "Glioblastoma"^^ . _:vb676971 . _:vb763764 _:vb676959 . _:vb676965 . _:vb676971 . _:vb763770 _:vb676965 . _:vb763771 _:vb676966 . _:vb763774 _:vb763775 . _:vb676968 . "Grade IV Astrocytic NeoplasmSYNCI" . _:vb676968 . . _:vb676969 . _:vb676969 . _:vb763772 _:vb763773 . _:vb730454 _:vb763761 . _:vb763768 _:vb676963 . "C3058"^^ . _:vb763769 _:vb676964 . _:vb730454 . _:vb763773 _:vb763774 . "GBMPTNCI-GLOSSCDR0000539131" . _:vb763773 _:vb676968 . _:vb676967 . _:vb763761 _:vb763762 . "GlioblastomaPTNCI" . _:vb676972 . _:vb676972 . "The most malignant astrocytic tumor (WHO grade IV). It is composed of poorly differentiated neoplastic astrocytes and it is characterized by the presence of cellular polymorphism, nuclear atypia, brisk mitotic activity, vascular thrombosis, microvascular proliferation and necrosis. It typically affects adults and is preferentially located in the cerebral hemispheres. It may develop from diffuse astrocytoma WHO grade II or anaplastic astrocytoma (secondary glioblastoma), but more frequently, it manifests after a short clinical history de novo, without evidence of a less malignant precursor lesion (primary glioblastoma). Two histologic variants are recognized: giant cell glioblastoma and gliosarcoma. (WHO)NCI" .