. "Chemical Viewed Functionally"^^ . "CHEBI:61115"^^ . "Histone_Deacetylase_Inhibitor"^^ . "C1946"^^ . "histone deacetylase inhibitorPTNCI-GLOSSCDR0000472896" . . "Histone Deacetylase Inhibitor"^^ . "Any substance that inhibits histone deacetylase, an enzyme that catalyzes the removal of acetyl groups from core histones. Inhibition of histone deacetylase can result in hyperacetylation of histones, with an effect on gene expression and cell differentiation.NCI" . "Histone Deacetylase Inhibitor"^^ . "HDAC inhibitorPTNCI-GLOSSCDR0000473970" . "Histone Deacetylase InhibitorPTNCI" . "HDAC AgentSYNCI" . "C1512474"^^ . . "A substance that causes a chemical change that stops tumor cells from dividing. HDAC inhibitors are being studied in the treatment of cancer.NCI-GLOSS" .