"Chemical Viewed Functionally"^^ . "C0594374"^^ . "Topoisomerase-I InhibitorPTNCI" . "Topoisomerase-I Inhibitor"^^ . . "CHEBI:50276"^^ . "Topoisomerase-I Inhibitor"^^ . "Any substance that inhibits topoisomerase-I, a topoisomerase that relieves torsional stress in a DNA molecule by cutting only one strand of the DNA double helix. Inhibition of topoisomerase-I causes DNA damage, inhibition of DNA replication, and apoptosis.NCI" . "C1904"^^ . "Topoisomerase-I_Inhibitor"^^ . "Topoisomerase-I InhibitorsSYNCI" . .