"41410"^^ . "Roquinimex"^^ . "Roquinimex"^^ . "LS 2616CNNCI" . "1,2-Dihydro-4-hydroxy-N,1-dimethyl-2-oxo-N-phenyl-3-quinolinecarboxamidePTDCP09087" . "RoquinimexPTNCI" . . "Organic Chemical"^^ . "ROQUINIMEXPTFDA372T2944C0" . . "Pharmacologic Substance"^^ . "FCF 89CNNCI" . "1,2-Dihydro-4-hydroxy-N,1-dimethyl-2-oxo-3-quinolinecarboxanilideSNNCI" . "84088-42-6"^^ . "C18H16N2O3"^^ . "FDA"^^ . "1,2-Dihydro-4-hydroxy-N,1-dimethyl-2-oxo-N-phenyl-3-quinolinecarboxamideSNNCI" . . "LinomideBRNCI" . "C0244748"^^ . . "372T2944C0"^^ . "A quinoline-3-carboxamide with potential antineoplastic activity. Roquinimex inhibits endothelial cell proliferation, migration, and basement membrane invasion; reduces the secretion of the angiogenic factor tumor necrosis factor alpha by tumor-associated macrophages (TAMs); and inhibits angiogenesis. This agent is also an immune modulator that appears to alter cytokine profiles and enhance the activity of T cells, natural killer cells, and macrophages. (NCI04)NCI" . . "Roquinimex"^^ . "41410"^^ . "N-Phenyl-N-methyl-1,2-dihydro-4-hydroxy-1-methyl-2-oxoquinoline-3-carboxamideSNNCI" . "C1519"^^ .