_:vb719341 . _:vb640573 . _:vb719340 . _:vb719342 . _:vb719342 . _:vb792722 _:vb719339 . _:vb792723 _:vb719340 . "42153"^^ . _:vb719339 . "Amino Acid, Peptide, or Protein"^^ . "Pharmacologic Substance"^^ . _:vb719340 . _:vb792724 _:vb719341 . "AIDS-related lymphoma; Colorectal cancer; Kidney cancer; Lung carcinoma; Melanoma; Mycosis fungoides; Neuroblastoma; Non Hodgkins lymphoma; Ovarian epithelial cancer; Peritoneal cavity cancer; Renal cell cancer; Sarcomas; Unspecified solid tumors"^^ . _:vb792725 _:vb719342 . _:vb719341 . "42153"^^ . "Recombinant Interleukin-12PTNCI" . _:vb640573 _:vb731395 . _:vb792725 . "IL-12PTNCI-GLOSSCDR0000044418" . "Recombinant Interleukin-12"^^ . _:vb719341 . "C1380"^^ . "672423"^^ . _:vb792723 _:vb792724 . _:vb731395 _:vb792722 . _:vb792722 _:vb792723 . _:vb640573 . _:vb792724 _:vb792725 . "Ro 24-7472CNNCI" . "Therapeutic_Interleukin-12"^^ . "Recombinant human interleukin-12 (IL-12) cytokineSYNCI" . _:vb719340 . "A recombinant form of the endogenous heterodimeric cytokine interleukin-12 with potential antineoplastic activity. Recombinant interleukin-12 binds to and activates its cell-surface receptor, stimulating the production of interferon-gamma (IFN) which, in turn, induces IFN-gamma-inducible protein-10 (IP-10) and so inhibits tumor angiogenesis. (NCI04)NCI" . . _:vb719342 . "Cytotoxic Lymphocyte Maturation FactorSYNCI" . "Natural Killer Cell Stimulatory FactorSYNCI" . "interleukin-12PTNCI-GLOSSCDR0000045426" . "IL-12ABNCI" . "Interleukin-12SYDTPNSC0672423" . . _:vb719339 . "C1524115"^^ . _:vb719339 . "One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-12 is made mainly by B lymphocytes and macrophages. It causes other immune cells to make cytokines and increases the growth of T lymphocytes. It may also block the growth of new blood vessels. Interleukin-12 made in the laboratory is used as a biological response modifier to boost the immune system in cancer therapy. Interleukin-12 is a type of cytokine.NCI-GLOSS" . "Interleukin 12PTDCP09122" . "187348-17-0"^^ . _:vb731395 . "Recombinant Interleukin-12"^^ .